Q14K (p.Gln14Lys) variant of YAP1 (Transcriptional coactivator YAP1)
Q14K (p.Gln14Lys) in YAP1 (Transcriptional coactivator YAP1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data, experimental measurements, and structural context.
Q14K (p.Gln14Lys) variant details
- p.Gln14Lys
- TOPMed rs1182593083
- gnomAD rs1182593083
- Missense
- Variant Prioritization Score for Impact Estimate 0.237
- REVEL 0.08
- CADD 22.20
- PolyPhen-2 0.01
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 4.4e-05)
- Structural context available
- YAP1 WW domain domainome 1.0: score -0.666