Q10P (p.Gln10Pro) variant of YAP1 (Transcriptional coactivator YAP1)
Q10P (p.Gln10Pro) in YAP1 (Transcriptional coactivator YAP1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
Q10P (p.Gln10Pro) variant details
- p.Gln10Pro
- gnomAD 11-102110877-A-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.173
- REVEL 0.04
- CADD 22.40
- PolyPhen-2 0.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9.8e-07)
- Structural context available
- YAP1 WW domain domainome 1.0: score -0.958
- Literature evidence available