Q10K (p.Gln10Lys) variant of YAP1 (Transcriptional coactivator YAP1)
Q10K (p.Gln10Lys) in YAP1 (Transcriptional coactivator YAP1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data, experimental measurements, and structural context.
Q10K (p.Gln10Lys) variant details
- p.Gln10Lys
- gnomAD rs1323319846
- Missense
- Variant Prioritization Score for Impact Estimate 0.219
- REVEL 0.06
- CADD 21.40
- PolyPhen-2 0.00
- SIFT 0.00
- Most common in the Middle Eastern population (allele frequency 0.00028)
- Structural context available
- YAP1 WW domain domainome 1.0: score -0.958