P8Q (p.Pro8Gln) variant of YAP1 (Transcriptional coactivator YAP1)
P8Q (p.Pro8Gln) in YAP1 (Transcriptional coactivator YAP1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
P8Q (p.Pro8Gln) variant details
- p.Pro8Gln
- gnomAD 11-102110871-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.184
- REVEL 0.08
- CADD 23.50
- PolyPhen-2 0.96
- SIFT 0.00
- Population evidence available
- Structural context available
- YAP1 WW domain domainome 1.0: score -0.722
- Literature evidence available