P3T (p.Pro3Thr) variant of YAP1 (Transcriptional coactivator YAP1)
P3T (p.Pro3Thr) in YAP1 (Transcriptional coactivator YAP1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data, experimental measurements, and structural context.
P3T (p.Pro3Thr) variant details
- p.Pro3Thr
- TOPMed rs1319669560
- gnomAD rs1319669560
- Missense
- Variant Prioritization Score for Impact Estimate 0.181
- REVEL 0.03
- CADD 19.40
- PolyPhen-2 0.01
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9.9e-07)
- Structural context available
- YAP1 WW domain domainome 1.0: score -0.7