P30L (p.Pro30Leu) variant of YAP1 (Transcriptional coactivator YAP1)
P30L (p.Pro30Leu) in YAP1 (Transcriptional coactivator YAP1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
P30L (p.Pro30Leu) variant details
- p.Pro30Leu
- gnomAD 11-102110937-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.162
- REVEL 0.04
- CADD 21.20
- PolyPhen-2 0.01
- SIFT 0.01
- Population evidence available
- Structural context available
- YAP1 WW domain domainome 1.0: score -0.61
- Literature evidence available