P24Q (p.Pro24Gln) variant of YAP1 (Transcriptional coactivator YAP1)
P24Q (p.Pro24Gln) in YAP1 (Transcriptional coactivator YAP1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
P24Q (p.Pro24Gln) variant details
- p.Pro24Gln
- gnomAD 11-102110919-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.226
- REVEL 0.11
- CADD 18.00
- PolyPhen-2 0.23
- SIFT 0.12
- Population evidence available
- Structural context available
- YAP1 WW domain domainome 1.0: score -0.813
- Literature evidence available