P23T (p.Pro23Thr) variant of YAP1 (Transcriptional coactivator YAP1)
P23T (p.Pro23Thr) in YAP1 (Transcriptional coactivator YAP1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data, experimental measurements, and structural context.
P23T (p.Pro23Thr) variant details
- p.Pro23Thr
- cosmic curated COSV56776
- Missense
- Variant Prioritization Score for Impact Estimate 0.14
- REVEL 0.04
- CADD 12.70
- PolyPhen-2 0.00
- SIFT 0.20
- Population evidence available
- Structural context available
- YAP1 WW domain domainome 1.0: score -0.877