P20T (p.Pro20Thr) variant of YAP1 (Transcriptional coactivator YAP1)
P20T (p.Pro20Thr) in YAP1 (Transcriptional coactivator YAP1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data, experimental measurements, and structural context.
P20T (p.Pro20Thr) variant details
- p.Pro20Thr
- cosmic curated COSV99176
- Missense
- Variant Prioritization Score for Impact Estimate 0.119
- REVEL 0.04
- CADD 14.60
- PolyPhen-2 0.01
- SIFT 0.20
- Population evidence available
- Structural context available
- YAP1 WW domain domainome 1.0: score -0.44