P20H (p.Pro20His) variant of YAP1 (Transcriptional coactivator YAP1)

Name: YAP1 P20H (p.Pro20His) variant | CATVariant
Creator: Center for Precision Medicine and Data Sciences
Published: 2026-08-19
License: https://catvariant.com/terms-of-use

P20H (p.Pro20His) in YAP1 (Transcriptional coactivator YAP1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.

P20H (p.Pro20His) variant details

p.Pro20His
gnomAD 11-102110907-C-A
Missense
Variant Prioritization Score for Impact Estimate 0.19
REVEL 0.08
CADD 17.60
PolyPhen-2 0.13
SIFT 0.12
Population evidence available
Structural context available
YAP1 WW domain domainome 1.0: score -0.44
Literature evidence available