P20A (p.Pro20Ala) variant of YAP1 (Transcriptional coactivator YAP1)
P20A (p.Pro20Ala) in YAP1 (Transcriptional coactivator YAP1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
P20A (p.Pro20Ala) variant details
- p.Pro20Ala
- gnomAD 11-102110906-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.116
- REVEL 0.04
- CADD 13.10
- PolyPhen-2 0.00
- SIFT 0.35
- Most common in the REMAINING population (allele frequency 1.9e-05)
- Structural context available
- YAP1 WW domain domainome 1.0: score -0.44
- Literature evidence available