P19R (p.Pro19Arg) variant of YAP1 (Transcriptional coactivator YAP1)
P19R (p.Pro19Arg) in YAP1 (Transcriptional coactivator YAP1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data, experimental measurements, and structural context.
P19R (p.Pro19Arg) variant details
- p.Pro19Arg
- TOPMed rs1415100005
- gnomAD rs1415100005
- Missense
- Variant Prioritization Score for Impact Estimate 0.189
- REVEL 0.02
- CADD 21.90
- PolyPhen-2 0.01
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 2.9e-05)
- Structural context available
- YAP1 WW domain domainome 1.0: score -0.686