P13R (p.Pro13Arg) variant of YAP1 (Transcriptional coactivator YAP1)
P13R (p.Pro13Arg) in YAP1 (Transcriptional coactivator YAP1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data, experimental measurements, and structural context.
P13R (p.Pro13Arg) variant details
- p.Pro13Arg
- TOPMed rs1255203435
- gnomAD rs1255203435
- Missense
- Variant Prioritization Score for Impact Estimate 0.243
- REVEL 0.04
- CADD 22.60
- PolyPhen-2 0.01
- SIFT 0.01
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available
- YAP1 WW domain domainome 1.0: score -1.16