P11S (p.Pro11Ser) variant of YAP1 (Transcriptional coactivator YAP1)
P11S (p.Pro11Ser) in YAP1 (Transcriptional coactivator YAP1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes population frequency data, experimental measurements, and structural context.
P11S (p.Pro11Ser) variant details
- p.Pro11Ser
- gnomAD rs1281367129
- Missense
- Variant Prioritization Score for Impact Estimate 0.109
- REVEL 0.01
- CADD 17.50
- PolyPhen-2 0.02
- SIFT 0.00
- Most common in the REMAINING population (allele frequency 3.9e-05)
- Structural context available
- YAP1 WW domain domainome 1.0: score -0.497