G4R (p.Gly4Arg) variant of YAP1 (Transcriptional coactivator YAP1)
G4R (p.Gly4Arg) in YAP1 (Transcriptional coactivator YAP1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data, experimental measurements, and structural context.
G4R (p.Gly4Arg) variant details
- p.Gly4Arg
- TOPMed rs972415996
- Missense
- Variant Prioritization Score for Impact Estimate 0.25
- REVEL 0.06
- CADD 22.40
- PolyPhen-2 0.00
- SIFT 0.00
- Most common in the REMAINING population (allele frequency 2e-05)
- Structural context available
- YAP1 WW domain domainome 1.0: score -0.302