G28S (p.Gly28Ser) variant of YAP1 (Transcriptional coactivator YAP1)
G28S (p.Gly28Ser) in YAP1 (Transcriptional coactivator YAP1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data, experimental measurements, and structural context.
G28S (p.Gly28Ser) variant details
- p.Gly28Ser
- TOPMed rs1942855577
- gnomAD rs1942855577
- Missense
- Variant Prioritization Score for Impact Estimate 0.235
- REVEL 0.07
- CADD 18.90
- PolyPhen-2 0.00
- SIFT 0.47
- Population evidence available
- Structural context available
- YAP1 WW domain domainome 1.0: score -0.369