G28R (p.Gly28Arg) variant of YAP1 (Transcriptional coactivator YAP1)
G28R (p.Gly28Arg) in YAP1 (Transcriptional coactivator YAP1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data, experimental measurements, and structural context.
G28R (p.Gly28Arg) variant details
- p.Gly28Arg
- TOPMed rs1942855577
- gnomAD rs1942855577
- Missense
- Variant Prioritization Score for Impact Estimate 0.237
- REVEL 0.08
- CADD 17.20
- PolyPhen-2 0.00
- SIFT 0.88
- Most common in the REMAINING population (allele frequency 1.9e-05)
- Structural context available
- YAP1 WW domain domainome 1.0: score -0.369