G28D (p.Gly28Asp) variant of YAP1 (Transcriptional coactivator YAP1)
G28D (p.Gly28Asp) in YAP1 (Transcriptional coactivator YAP1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
G28D (p.Gly28Asp) variant details
- p.Gly28Asp
- gnomAD 11-102110931-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.155
- REVEL 0.05
- CADD 17.00
- PolyPhen-2 0.00
- SIFT 0.21
- Population evidence available
- Structural context available
- YAP1 WW domain domainome 1.0: score -0.369
- Literature evidence available