G26R (p.Gly26Arg) variant of YAP1 (Transcriptional coactivator YAP1)
G26R (p.Gly26Arg) in YAP1 (Transcriptional coactivator YAP1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data, experimental measurements, and structural context.
G26R (p.Gly26Arg) variant details
- p.Gly26Arg
- cosmic curated COSV99176
- TOPMed rs1277114008
- gnomAD rs1277114008
- Missense
- Variant Prioritization Score for Impact Estimate 0.238
- REVEL 0.08
- CADD 19.70
- PolyPhen-2 0.00
- SIFT 0.07
- Most common in the Latino/Admixed American population (allele frequency 4.9e-05)
- Structural context available
- YAP1 WW domain domainome 1.0: score -0.583