G26E (p.Gly26Glu) variant of YAP1 (Transcriptional coactivator YAP1)
G26E (p.Gly26Glu) in YAP1 (Transcriptional coactivator YAP1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data, experimental measurements, and structural context.
G26E (p.Gly26Glu) variant details
- p.Gly26Glu
- gnomAD rs1188136705
- Missense
- Variant Prioritization Score for Impact Estimate 0.194
- REVEL 0.07
- CADD 18.40
- PolyPhen-2 0.00
- SIFT 0.53
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available
- YAP1 WW domain domainome 1.0: score -0.583