G17W (p.Gly17Trp) variant of YAP1 (Transcriptional coactivator YAP1)
G17W (p.Gly17Trp) in YAP1 (Transcriptional coactivator YAP1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
G17W (p.Gly17Trp) variant details
- p.Gly17Trp
- gnomAD 11-102110897-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.277
- REVEL 0.12
- CADD 25.70
- PolyPhen-2 0.68
- SIFT 0.00
- Most common in the Finnish in Finland (FIN) population (allele frequency 2.5e-05)
- Structural context available
- YAP1 WW domain domainome 1.0: score -1.03
- Literature evidence available