G17R (p.Gly17Arg) variant of YAP1 (Transcriptional coactivator YAP1)
G17R (p.Gly17Arg) in YAP1 (Transcriptional coactivator YAP1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data, experimental measurements, and structural context.
G17R (p.Gly17Arg) variant details
- p.Gly17Arg
- ExAC rs765528842
- gnomAD rs765528842
- Missense
- Variant Prioritization Score for Impact Estimate 0.208
- REVEL 0.04
- CADD 23.20
- PolyPhen-2 0.00
- SIFT 0.00
- Most common in the South Asian population (allele frequency 4.5e-05)
- Structural context available
- YAP1 WW domain domainome 1.0: score -1.03