G15S (p.Gly15Ser) variant of YAP1 (Transcriptional coactivator YAP1)
G15S (p.Gly15Ser) in YAP1 (Transcriptional coactivator YAP1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data, experimental measurements, and structural context.
G15S (p.Gly15Ser) variant details
- p.Gly15Ser
- TOPMed rs1428291984
- gnomAD rs1428291984
- Missense
- Variant Prioritization Score for Impact Estimate 0.216
- REVEL 0.06
- CADD 20.00
- PolyPhen-2 0.00
- SIFT 0.08
- Most common in the Latino/Admixed American population (allele frequency 6.6e-05)
- Structural context available
- YAP1 WW domain domainome 1.0: score -0.616