Y139H (p.Tyr139His) variant of XRCC3 (DNA repair protein XRCC3)
Y139H (p.Tyr139His) in XRCC3 (DNA repair protein XRCC3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.68 / 1. The record also includes population frequency data and structural context.
Y139H (p.Tyr139His) variant details
- p.Tyr139His
- Ensembl rs2151931542
- Missense
- Variant Prioritization Score for Impact Estimate 0.675
- REVEL 0.70
- CADD 27.30
- PolyPhen-2 0.99
- SIFT 0.00
- Population evidence available
- Structural context available