T64I (p.Thr64Ile) variant of XRCC3 (DNA repair protein XRCC3)
T64I (p.Thr64Ile) in XRCC3 (DNA repair protein XRCC3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.53 / 1. The record also includes population frequency data and structural context.
T64I (p.Thr64Ile) variant details
- p.Thr64Ile
- ExAC rs748448131
- gnomAD rs748448131
- Missense
- Variant Prioritization Score for Impact Estimate 0.531
- REVEL 0.34
- CADD 29.00
- PolyPhen-2 0.54
- SIFT 0.03
- Most common in the South Asian population (allele frequency 2.3e-05)
- Structural context available