S83R (p.Ser83Arg) variant of XRCC3 (DNA repair protein XRCC3)
S83R (p.Ser83Arg) in XRCC3 (DNA repair protein XRCC3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data and structural context.
S83R (p.Ser83Arg) variant details
- p.Ser83Arg
- TOPMed rs987650208
- gnomAD rs987650208
- Missense
- Variant Prioritization Score for Impact Estimate 0.395
- REVEL 0.39
- CADD 23.10
- PolyPhen-2 0.60
- SIFT 0.05
- Population evidence available
- Structural context available