S60N (p.Ser60Asn) variant of XRCC3 (DNA repair protein XRCC3)
S60N (p.Ser60Asn) in XRCC3 (DNA repair protein XRCC3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.03 / 1. The record also includes population frequency data and structural context.
S60N (p.Ser60Asn) variant details
- p.Ser60Asn
- cosmic curated COSV61399
- ExAC rs758533921
- gnomAD rs758533921
- Missense
- Variant Prioritization Score for Impact Estimate 0.033
- REVEL 0.01
- CADD 0.36
- PolyPhen-2 0.00
- SIFT 0.62
- Most common in the South Asian population (allele frequency 0.00016)
- Structural context available