S42Y (p.Ser42Tyr) variant of XRCC3 (DNA repair protein XRCC3)
S42Y (p.Ser42Tyr) in XRCC3 (DNA repair protein XRCC3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.58 / 1. The record also includes population frequency data and structural context.
S42Y (p.Ser42Tyr) variant details
- p.Ser42Tyr
- TOPMed rs569323871
- Missense
- Variant Prioritization Score for Impact Estimate 0.577
- REVEL 0.43
- CADD 25.60
- PolyPhen-2 0.89
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available