S31P (p.Ser31Pro) variant of XRCC3 (DNA repair protein XRCC3)
S31P (p.Ser31Pro) in XRCC3 (DNA repair protein XRCC3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data and structural context.
S31P (p.Ser31Pro) variant details
- p.Ser31Pro
- ExAC rs781514761
- TOPMed rs781514761
- gnomAD rs781514761
- Missense
- Variant Prioritization Score for Impact Estimate 0.384
- REVEL 0.23
- CADD 22.40
- PolyPhen-2 0.41
- SIFT 0.06
- Most common in the Latino/Admixed American population (allele frequency 0.00092)
- Structural context available