S109G (p.Ser109Gly) variant of XRCC3 (DNA repair protein XRCC3)
S109G (p.Ser109Gly) in XRCC3 (DNA repair protein XRCC3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
S109G (p.Ser109Gly) variant details
- p.Ser109Gly
- TOPMed rs2083462171
- Missense
- Variant Prioritization Score for Impact Estimate 0.338
- REVEL 0.22
- CADD 22.50
- PolyPhen-2 0.44
- SIFT 0.01
- Population evidence available
- Structural context available