R58Q (p.Arg58Gln) variant of XRCC3 (DNA repair protein XRCC3)
R58Q (p.Arg58Gln) in XRCC3 (DNA repair protein XRCC3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data and structural context.
R58Q (p.Arg58Gln) variant details
- p.Arg58Gln
- 1000Genomes rs139963722
- ESP rs139963722
- ExAC rs139963722
- TOPMed rs139963722
- Missense
- Variant Prioritization Score for Impact Estimate 0.142
- REVEL 0.13
- CADD 13.00
- PolyPhen-2 0.11
- SIFT 0.10
- Most common in the 1KG:GWD population (allele frequency 0.013)
- Structural context available