R58G (p.Arg58Gly) variant of XRCC3 (DNA repair protein XRCC3)
R58G (p.Arg58Gly) in XRCC3 (DNA repair protein XRCC3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data and structural context.
R58G (p.Arg58Gly) variant details
- p.Arg58Gly
- ESP rs143410843
- ExAC rs143410843
- TOPMed rs143410843
- gnomAD rs143410843
- Missense
- Variant Prioritization Score for Impact Estimate 0.385
- REVEL 0.28
- CADD 23.20
- PolyPhen-2 0.66
- SIFT 0.01
- Most common in the Latino/Admixed American population (allele frequency 0.00011)
- Structural context available