R128Q (p.Arg128Gln) variant of XRCC3 (DNA repair protein XRCC3)
R128Q (p.Arg128Gln) in XRCC3 (DNA repair protein XRCC3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.03 / 1. The record also includes population frequency data and structural context.
R128Q (p.Arg128Gln) variant details
- p.Arg128Gln
- cosmic curated COSV10466
- ExAC rs754599485
- TOPMed rs754599485
- gnomAD rs754599485
- Missense
- Variant Prioritization Score for Impact Estimate 0.0319
- REVEL 0.01
- CADD 0.05
- PolyPhen-2 0.02
- SIFT 0.31
- Most common in the REMAINING population (allele frequency 0.00048)
- Structural context available