R108H (p.Arg108His) variant of XRCC3 (DNA repair protein XRCC3)
R108H (p.Arg108His) in XRCC3 (DNA repair protein XRCC3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.06 / 1. The record also includes population frequency data and structural context.
R108H (p.Arg108His) variant details
- p.Arg108His
- 1000Genomes rs1338448676
- TOPMed rs1338448676
- gnomAD rs1338448676
- Missense
- Variant Prioritization Score for Impact Estimate 0.0624
- REVEL 0.02
- CADD 0.17
- PolyPhen-2 0.01
- SIFT 0.11
- Most common in the 1KG:MSL population (allele frequency 0.0063)
- Structural context available