Q125* (p.Gln125Ter) variant of XRCC3 (DNA repair protein XRCC3)
Q125* (p.Gln125Ter) in XRCC3 (DNA repair protein XRCC3) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.86 / 1. The record also includes population frequency data and structural context.
Q125* (p.Gln125Ter) variant details
- p.Gln125Ter
- TOPMed rs1324691444
- gnomAD rs1324691444
- Stop Gained
- Variant Prioritization Score for Impact Estimate 0.863
- CADD 41.00
- Most common in the Latino/Admixed American population (allele frequency 2.6e-05)
- Structural context available