Q119L (p.Gln119Leu) variant of XRCC3 (DNA repair protein XRCC3)
Q119L (p.Gln119Leu) in XRCC3 (DNA repair protein XRCC3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.52 / 1. The record also includes population frequency data and structural context.
Q119L (p.Gln119Leu) variant details
- p.Gln119Leu
- gnomAD rs1213272135
- Missense
- Variant Prioritization Score for Impact Estimate 0.522
- REVEL 0.50
- CADD 27.20
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the East Asian population (allele frequency 2.7e-05)
- Structural context available