P98T (p.Pro98Thr) variant of XRCC3 (DNA repair protein XRCC3)
P98T (p.Pro98Thr) in XRCC3 (DNA repair protein XRCC3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.55 / 1. The record also includes population frequency data and structural context.
P98T (p.Pro98Thr) variant details
- p.Pro98Thr
- gnomAD rs1290556142
- Missense
- Variant Prioritization Score for Impact Estimate 0.549
- REVEL 0.40
- CADD 24.40
- PolyPhen-2 0.77
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 9.3e-07)
- Structural context available