P44R (p.Pro44Arg) variant of XRCC3 (DNA repair protein XRCC3)
P44R (p.Pro44Arg) in XRCC3 (DNA repair protein XRCC3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data and structural context.
P44R (p.Pro44Arg) variant details
- p.Pro44Arg
- gnomAD rs1400707283
- Missense
- Variant Prioritization Score for Impact Estimate 0.119
- REVEL 0.04
- CADD 7.75
- PolyPhen-2 0.01
- SIFT 0.35
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available