L97V (p.Leu97Val) variant of XRCC3 (DNA repair protein XRCC3)
L97V (p.Leu97Val) in XRCC3 (DNA repair protein XRCC3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
L97V (p.Leu97Val) variant details
- p.Leu97Val
- gnomAD rs1413953615
- Missense
- Variant Prioritization Score for Impact Estimate 0.273
- REVEL 0.09
- CADD 18.90
- PolyPhen-2 0.20
- SIFT 0.15
- Most common in the Non-Finnish European population (allele frequency 9.3e-07)
- Structural context available