L118M (p.Leu118Met) variant of XRCC3 (DNA repair protein XRCC3)
L118M (p.Leu118Met) in XRCC3 (DNA repair protein XRCC3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
L118M (p.Leu118Met) variant details
- p.Leu118Met
- ExAC rs768997440
- gnomAD rs768997440
- Missense
- Variant Prioritization Score for Impact Estimate 0.334
- REVEL 0.20
- CADD 22.50
- PolyPhen-2 0.98
- SIFT 0.14
- Population evidence available
- Structural context available