K72R (p.Lys72Arg) variant of XRCC3 (DNA repair protein XRCC3)
K72R (p.Lys72Arg) in XRCC3 (DNA repair protein XRCC3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.06 / 1. The record also includes population frequency data and structural context.
K72R (p.Lys72Arg) variant details
- p.Lys72Arg
- gnomAD rs1178462888
- Missense
- Variant Prioritization Score for Impact Estimate 0.0569
- REVEL 0.05
- CADD 0.72
- PolyPhen-2 0.02
- SIFT 0.50
- Most common in the East Asian population (allele frequency 2.8e-05)
- Structural context available