H29Y (p.His29Tyr) variant of XRCC3 (DNA repair protein XRCC3)
H29Y (p.His29Tyr) in XRCC3 (DNA repair protein XRCC3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data and structural context.
H29Y (p.His29Tyr) variant details
- p.His29Tyr
- 1000Genomes rs546983534
- ExAC rs546983534
- TOPMed rs546983534
- gnomAD rs546983534
- Missense
- Variant Prioritization Score for Impact Estimate 0.224
- REVEL 0.05
- CADD 10.60
- PolyPhen-2 0.11
- SIFT 0.25
- Most common in the 1KG:KHV population (allele frequency 0.005)
- Structural context available