G85D (p.Gly85Asp) variant of XRCC3 (DNA repair protein XRCC3)
G85D (p.Gly85Asp) in XRCC3 (DNA repair protein XRCC3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.72 / 1. The record also includes population frequency data and structural context.
G85D (p.Gly85Asp) variant details
- p.Gly85Asp
- TOPMed rs1241591256
- gnomAD rs1241591256
- Missense
- Variant Prioritization Score for Impact Estimate 0.716
- REVEL 0.68
- CADD 25.40
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available