G32E (p.Gly32Glu) variant of XRCC3 (DNA repair protein XRCC3)
G32E (p.Gly32Glu) in XRCC3 (DNA repair protein XRCC3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
G32E (p.Gly32Glu) variant details
- p.Gly32Glu
- TOPMed rs1223201445
- gnomAD rs1223201445
- Missense
- Variant Prioritization Score for Impact Estimate 0.178
- REVEL 0.12
- CADD 15.10
- PolyPhen-2 0.12
- SIFT 0.05
- Most common in the East Asian population (allele frequency 5e-05)
- Structural context available