G136A (p.Gly136Ala) variant of XRCC3 (DNA repair protein XRCC3)
G136A (p.Gly136Ala) in XRCC3 (DNA repair protein XRCC3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1. The record also includes population frequency data and structural context.
G136A (p.Gly136Ala) variant details
- p.Gly136Ala
- 1000Genomes rs200124946
- ExAC rs200124946
- TOPMed rs200124946
- gnomAD rs200124946
- Missense
- Variant Prioritization Score for Impact Estimate 0.507
- REVEL 0.24
- CADD 33.00
- PolyPhen-2 0.90
- SIFT 0.00
- Most common in the 1KG:TSI population (allele frequency 0.0049)
- Structural context available