G112W (p.Gly112Trp) variant of XRCC3 (DNA repair protein XRCC3)
G112W (p.Gly112Trp) in XRCC3 (DNA repair protein XRCC3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.81 / 1. The record also includes population frequency data and structural context.
G112W (p.Gly112Trp) variant details
- p.Gly112Trp
- ExAC rs773795652
- TOPMed rs773795652
- gnomAD rs773795652
- Missense
- Variant Prioritization Score for Impact Estimate 0.813
- REVEL 0.85
- CADD 25.00
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9.2e-07)
- Structural context available