G112R (p.Gly112Arg) variant of XRCC3 (DNA repair protein XRCC3)
G112R (p.Gly112Arg) in XRCC3 (DNA repair protein XRCC3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.82 / 1. The record also includes population frequency data and structural context.
G112R (p.Gly112Arg) variant details
- p.Gly112Arg
- ExAC rs773795652
- TOPMed rs773795652
- gnomAD rs773795652
- Missense
- Variant Prioritization Score for Impact Estimate 0.823
- REVEL 0.87
- CADD 24.50
- PolyPhen-2 1.00
- SIFT 0.00
- Population evidence available
- Structural context available