G101S (p.Gly101Ser) variant of XRCC3 (DNA repair protein XRCC3)
G101S (p.Gly101Ser) in XRCC3 (DNA repair protein XRCC3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data and structural context.
G101S (p.Gly101Ser) variant details
- p.Gly101Ser
- cosmic curated COSV61398
- ExAC rs752288087
- TOPMed rs752288087
- gnomAD rs752288087
- Missense
- Variant Prioritization Score for Impact Estimate 0.38
- REVEL 0.26
- CADD 23.70
- PolyPhen-2 0.94
- SIFT 0.04
- Most common in the South Asian population (allele frequency 0.00041)
- Structural context available