F75L (p.Phe75Leu) variant of XRCC3 (DNA repair protein XRCC3)
F75L (p.Phe75Leu) in XRCC3 (DNA repair protein XRCC3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
F75L (p.Phe75Leu) variant details
- p.Phe75Leu
- Ensembl rs2151938349
- Missense
- Variant Prioritization Score for Impact Estimate 0.299
- REVEL 0.17
- CADD 15.50
- PolyPhen-2 0.01
- SIFT 0.50
- Population evidence available
- Structural context available