E73K (p.Glu73Lys) variant of XRCC3 (DNA repair protein XRCC3)
E73K (p.Glu73Lys) in XRCC3 (DNA repair protein XRCC3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data and structural context.
E73K (p.Glu73Lys) variant details
- p.Glu73Lys
- ExAC rs761300047
- TOPMed rs761300047
- Missense
- Variant Prioritization Score for Impact Estimate 0.143
- REVEL 0.08
- CADD 1.09
- PolyPhen-2 0.03
- SIFT 0.88
- Most common in the African/African-American population (allele frequency 3.2e-05)
- Structural context available